Mechanical Ventilation – ICU Reference Guide (Adult) 

1. Initial Ventilator Settings 

 
2. Safe Pressure Limits 


 
3. Oxygenation Targets (follow documented instruction of attending clinicians)
 

 
4. Ventilation (ABG Targets) 
 

 
5. Condition -Specific Adjustments 
 



6. Weaning Readiness 
 

 
7. Common Alarms – Quick Causes 

 
Notes:  
– Tidal volume should be based on Ideal Body Weight (IBW), not actual weight.  
– Adjust settings based on ABG results, lung mechanics, and clinical condition.  
– Always monitor plateau pressures to prevent ventilator-induced lung injury.  
– Use lung-protective strategies in ARDS or at-risk patients.  
– Weaning criteria should be assessed daily.